Although tumor accumulation rapidly decreases over time, there is still a fairly wide time window where high target-to-background ratios were observed.
Mucus clearance times in lung airways range from minutes to hours or significantly longer depending on deposition in the upper, middle, lower airways and on lung health, giving a wide time window for drug-loaded particle design to achieve controlled delivery to the epithelium.
Assuming stimulus delivery to 50% of the cell population, transitions from IP to AP are produced by a depolarizing stimulus if it is applied within a relatively wide time window located at mid-cycle (type X window) (upper panel Fig. 10A).
The study covered a wide time window, thus increasing generalizability and reducing potential seasonality bias.
This chronic arthritis resembles strongly the pathology in humans and provides a wide time window for clinical treatment studies.
Typically, the progress from adenoma to cancer takes several years, providing a wide time window for preventive intervention.
The on-exchange results suggest that a wide time window needs to be surveyed during on/off-exchange experiments for epitope mapping.
The relatively wide time window between admission and measurement of GE could have potentially weakened the strength of association between admission diagnosis and GE.
We were able to follow participants for over 40 years, which provided a unique wide time window for evaluating the risk of dyspnea severity and especially changes in dyspnea status on mortality.
Previous studies have shown a wide time window in the induction of e.g. noggin expression in different tissues after BMP treatment, ranging from 1 to 48 hours [ 42, 43].
