The detailed analysis of natural and anthropogenic processes at Nesher Ramla suggests a much wider spectrum of processes than previously reported for southern Levantine Paleolithic sites.
Actin polymerization and depolymerization plays a central role in controlling a wide spectrum of cellular processes.
Iron-bearing minerals are sensitive to a wide spectrum of natural processes and thus carry important environmental information.
β-Glucosidase enzymes (EC 3.2.1 3.2.3) hydrolyze sugars and are implicated in a wide spectrum of biological processes.
Ceramide, a sphingosine-based lipid molecule, has emerged as a key regulator of a wide spectrum of biological processes such as cellular differentiation, proliferation, apoptosis and senescence.
MicroRNAs (miRNAs) are small non-coding RNAs that modulate gene expression at post-transcriptional level for degradation of the target mRNAs or inhibiting translation of the encoded protein, playing critical roles in a wide spectrum of biological processes (Ambros, 2004).
Among a wide spectrum of diagenetic processes that have resulted in the formation of the Devonian fore-reef limestone of Germany or the Silurian limestone of Gotland, Sweden, for instance, cementation has been identified as the major phenomenon that governs the microstructure in carbonate rocks (Krebs 1969; Munnecke et al. 1997).
TNF is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation.
Thus, GSK3 by regulating several of its substrates participates in a wide spectrum of cellular processes, including glycogen metabolism, transcription, translation, cytoskeleton regulation, intracellular vesicular transport, cell cycle progression and apoptosis.
miRNAs are encoded by a diverse range of metazoan eukaryotes and plant species, and play important roles in a wide spectrum of biological processes such as embryonic development, cell differentiation, apoptosis, and oncogenesis [12].
