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We obtained from dbEST a number of mismatches roughly 5 times higher than the genome wide sequencing screens.
In this study we have employed a genome wide sequencing technique to identify mitochondrial mutations in adenoid cystic carcinoma.
Until recently, genome wide sequencing has been cost limited to relatively few species.
This approach shows promise for the analysis of data currently emerging from genome wide sequencing studies.
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In this study, we performed in vivo tumorigenicity tests (teratoma formation) and genome-wide sequencing analysis of undifferentiated hESCs i.e. SEES-1, -2 and -3 cells.
Genome-wide sequencing and high-throughput technologies have provided critical insights into the molecular basis of ICC while sparking a heated debate on the cellular origin.
However, the application of genome-wide sequencing in hereditary cancer syndromes has had mixed success, in part, due to complex nature of the underlying genetic architecture.
Using SKAT to analyze a genome-wide sequencing study of 1000 individuals, by segmenting the whole genome into 30 kb regions, requires only 7 hr on a laptop.
Genome-wide sequencing projects have identified a number of recurrently mutated genes, including unexpected alterations in the NOTCH pathway and chromatin related genes.
The recent genome-wide sequencing approach for many organisms has resulted in the discovery of many new proteins with increasingly obscure names.
The minimum number of overlapping BACs is sought for genome-wide sequencing coverage.
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