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However, genotyping these rare variants on a genome-wide scale will be a considerably more expensive endeavour than utilising GWA platforms.
Measuring some of the relevant quantities (e. g. protein expression) on a genome-wide scale will require advancement of experimental methods beyond what is possible today.
In such areas where baseline transmission is low, however, the absolute reductions in parasitaemia due to wide-scale net use will be relatively small raising questions on the cost-effectiveness of covering millions of people living in such settings in Africa with nets.
Large-scale genome-wide association studies will be helpful in dissecting out the genetic contribution in these cases.
The wider the width, the wider your ruffle will be.
Epigenome-wide analysis will be performed.
The wider costs will be captured separately.
The logistical process of "scaling up" will be made easier by consulting the wide range of farmer's associations, economic development associations, and local food networks in Southwestern Ontario.
But scaling up will be challenging.
The scales, however, will be unmoved.
While the wider pay bands will be maintained as a general reference, the set points between them will be abolished, with heads given the power to choose what within the scale a teacher is paid.
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