These high-throughput experimental techniques are designed to locate, in vivo and at a genome-wide scale, regions in the DNA where specific proteins bind, in particular TFs.
Although chromatin associated RNAs (CARs) were recently sequenced on a genome wide scale, the exact region of their association with chromatin has not been investigated [ 104].
We have characterized a large set of HER2+ BC in comparison to HER2- BC using a combination of molecular techniques to delineate the HER2-amplicon in high-detail, and to pinpoint, on a genome-wide scale, critical regions of focal amplifications, gains and losses that may be important for tumor development and reflect the heterogeneity of HER2+ BC.
The recent earthquake in January 2010 in the Haitian region reflects the wide scale of such damages [1].
Under French labeling rules, only tuber melansoporum can carry the name truffles, black truffles or truffes de Périgord, after the region that first marketed the mushroom on a wide scale.
They will assess the evolving situation in the Horn of Africa and "look at the root causes of the crisis and the longer-term needs of countries in the region to sustainably enhance livelihood resilience on a wide scale".
All these considerations make this part of the Pampean region an extraordinary place to understand the evolutionary processes in South America within a wide scale.
This study, performed on a genome-wide scale, detected QTL regions related to innate immune activation.
In an attempt to unravel the genetic architecture underlying the traits studied, we searched on a genome-wide scale for genomic regions homologous to the most important identified isoflavone biosynthetic genes.
At a genome-wide scale, the pericentromeric regions of the chromosomes and the heterochromatic fourth chromosome have a high proportion of TE-derived sequences, which are mostly incomplete and nested.
Conservation on a wide scale takes more than good ideas.
