The pattern of NBDM has the potential to alter on a genome-wide scale not only the deleteriousness of germline mutation but also, and perhaps even more importantly, that of somatic mutation, and therefore it could impact fitness by affecting not only the genetic quality of one's progeny but also, and perhaps mainly, individual viability.
If implemented on a wide scale, it would not only drastically alter the current method mix but also serve client needs much better and prevent unintended pregnancy more successfully.
The health professions would make a major contribution to the wide-scale health of children not only by curtailing psychiatric drugging, but also by offering the opportunity for parents to withdraw their children from these psychoactive substances.
This fine-scale refinement of a biologically defined sense of succession found wide applicability and enabled not only biochronological (or temporal) but also biofacies (spatial) understanding of the succession in question.
The development and large-scale validation of such genomic microsatellite markers in a genome-wide scale could be useful for not only genetic improvement of foxtail millet, but also for other under-utilized/orphan crop species for which very little or no genomic information is available.
When applied the tool on a genome-wide scale, we were able to not only recover correctly the majority of the histone genes used for training, but also predict a large number of other genes that share similar promoter structures with histone genes and we thus believe that they are likely to be coregulated and thus coexpressed with the histone genes.
Several aspects which anecdotally have shown to be a positive feature when attending for a DGA such as play specialists could be further explored on a wider scale between hospitals to see not only the impact on the day of the operation but on a short and long term basis in relation to anxiety, subsequent hospital or dental visits and recovery following a DGA.
These results suggest that individuals in a wide range of countries use social media to organize large-scale protests and not only at the height of protest events; coordination is a perpetual, systematic activity.
However, this existing technology hasn't been significantly employed in human CO research on a genome and transcriptome-wide scale; to date only one genome-wide expression study has been performed in rat [ 7].
However, similar approaches for profiling PKMT activity on a proteome-wide scale have not been described.
The impacts of introducing ICES in current distribution networks can be analyzed at different scales due to the wide range of influence exerted not only at the local but also at regional and global levels.
