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Comparison between the sensitivity analysis of the original model and the analytical predictions of the hybrid model (mapped back to the original model parameters), at small range and wide range parameter perturbations.
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Shifted dynamic matrix control (DMC) was found to be more robust with respect to all plant parameter variations, and therefore more suited than move suppressed DMC to control plants with wide ranging parameters.
Rather, GDP can be generated over a wide range of parameter values, provided certain parameter relationships are maintained.
To examine if this conclusion holds over a wide range of parameter values, we employed parameter sensitivity analysis (see Methods and Additional file 1: Figure S4).
We sampled 5000 sets of parameter values for the steady-state analysis over a wide range of parameter values (Supplementary Fig. S1).
To overcome the limitations of using specific values for a parameter set, we further performed LSA based on MCC over a wide range of parameter values (see Methods).
Comparisons over a wide range of parameter values are made.
These predictions are robust to a wide range of parameter values.
However, the results are quite robust, and are consistent over a wide range of parameter values.
The validity of this approach was confirmed through a numerical analysis over a wide range of parameter conditions.
Simulation results show that the algorithm converges for different desired output trajectories and a wide range of parameter configurations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com