As a management consultant he has achieved lasting impact with many types of corporations globally across a wide range of industries; the incremental value of the "Innovation Premium" achieved by the companies he has consulted to is calculated at over US$30 billion.
Different clonal CQR parasite lines display a wide range of CQ IC50 values, indicative of incremental and additive effects on drug phenotypes even when the pfcrt and pfmdr1 alleles are the same [23], [24].
Since there already exist established models (CRB-65, CURB-65, and PSI) with reasonable to good discriminative ability across a wide range of settings and only small incremental differences between these and newer scores, further research should mainly focus on why patients get misclassified and whether we can identify important variables within them to improve sensitivity of current models.
When it pounced, it flooded the market with a wide range of models that were constantly updated with incremental improvements at a speed its rivals found hard to match — a strategy best illustrated by its smartphone business.
26 A wide range of test protocols with different characteristics (ie, incremental stage durations and intensities, rest intervals and number of stages) are described elsewhere.
It investigates the relationships between personality and a wide range of important life outcomes, as well as the incremental validity of Grit when Big Five traits are accounted for.
Sensitivity analyses demonstrated that OLAI remains dominant and below the acceptable threshold of €30,000 [ 37] incremental cost per QALY across a wide range of analyses (Table 8), demonstrating the robustness of the results.
In this study, we rather looked for intra-patient linear correlation between non-invasive and invasive BP value changes during incremental high rates and within a wide range of BP values (from 41 to 190 mmHg).
In this scenario analysis the incremental cost-effectiveness ratio (ICER) remained stable within a wide range of assumptions on the duration of treatment effect (years): £10,966 (1 year), £16,515 (2 years), £20,369 (5 years), £20,298 (10 years), and £19,543 (20 years) per QALY gained.
Etanercept had a wide range of cost-efficacy estimate due to limited available data and was dominated in the incremental analysis.
