Previous studies employed a variety of methods to assess adherence, with different thresholds to define good adherence, and a wide range of adherent patients proportions were reported (from 20.7 to 93.5%) [ 10, 11, 29- 34].
First, sponsored "refill reminders" should encompass a broad range of adherence messages to patients.
Interviews with trial participants and professionals revealed a wide range of influences on adherence in the context of the trial and more generally, many of which shed light on the overall results.
Although patients were recruited from a wide range of clinical settings, adherence and health-related behaviours may be different in those willing to participate in a research study, compared with those who are not.
Our findings reveal that a wide range of factors contributed to treatment adherence (or non-adherence) in these pediatric long-term conditions.
A wide range of potential barriers to guideline adherence has been identified operating at different levels, such as the level of the physician, of the patient, the organizational context and the social and cultural context [16], [18] [20].
Studies assessing treatment practices looked at a wide range of factors, including drug selection, adherence to treatment protocols and dispensing without prescription.
The reviewed literature reported an unambiguous positive impact of community support on a wide range of aspects, including access, coverage, adherence, virological and immunological outcomes, patient retention and survival.
This latter category, of course, includes a wide range of patients with a suboptimal adherence behaviour, that is, those who might just occasionally miss few doses and those who might be recurrent nonadherers.
