Sentence examples for wide loss of from inspiring English sources

Intershop Communications, a maker of Internet commerce software, said it expected to report a surprisingly wide loss of 32 million euros ($30 million) in the fourth quarter because sales were little more than half what the company had forecast in October.

Then this system has produced too many prominent Americans revealed with a lack of character, greed and/or self-interest, a wide loss of public faith in many of our institutions and unpopular presidential campaigns to many Americans.

Consistent with previous studies, kyp mutant showed genome wide loss of methylation in CHG (∼42.1%) and CHH (∼21.7%), but not in CG (∼2%) contexts when compared to Col-0.

Recently, CRISPR/Cas9 gene editing has emerged as a powerful platform for unbiased genome-wide loss-of-function screening35,36.

Here we utilized genome-wide loss-of-function CRISPR screens to reveal genetic dependencies of eight PEL cell lines.

Here, we report results from two genome-wide loss-of-function TDP-43 toxicity suppressor screens in yeast.

The transgene-expressing shRNA approach has been adapted into large-scale resources for genome-wide loss-of-function screens, whereas focused studies on a narrow set of genes can be achieved by using individual shRNA constructs from these resources.

To map the genetic network underlying the regulation of nucleolar size and of Pol I-mediated transcription, we performed comparative, genome-wide loss-of-function analyses of nucleolar size in Saccharomyces cerevisiae and Drosophila melanogaster coupled with mass spectrometry-based analyses of the ribosomal DNA (rDNA) promoter.

RNAi HTS technology allows genome-wide loss-of-function screening and is broadly used in the identification of genes associated with specific phenotypes.

Among these, RNA interference (RNAi) can be used to expedite genome-wide loss-of-function (LOF) screens in mammalian systems [26], [27], [28], [29].

Moreover, genomic instability, as measured by genome-wide loss-of-heterozygosity (LOH) single nucleotide polymorphism (SNP) analysis, was greater in HNSCC samples with more pronounced LINE hypomethylation.