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Furthermore, the wide imbalance between the highest and lowest expressed genes (the top 1% genes contribute 27.8% of total mRNA) suggests the majority of mRNAs to be present at less than one copy per cell, consistent with recent reports of heterogeneity between individual cell transcriptomes [ 19].
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In a healthy market, the ratio is closer to 1 to 1. EXPORTS FALTER Hope for a trade-led recovery has also taken a hit, with the United States trade deficit surging in January to its widest imbalance in more than three years.
However, these frameworks may not be consistent with the future scenarios: The primary task of TSO is to avoid system-wide imbalance occurring, while the executive issue for DSO is to relieve the congestions in local network.
Until the authority and autonomy of women is accepted, theatre will register society's wider imbalances, says Harris.
Our economy falters because China is a "currency manipulator"; our renewable energy technology can't compete because the Chinese government is pouring heavy -- even illicit -- subsidies into China's renewable energy industries; and the wide trade imbalance is because Chinese traditionally have a lower rate of consumption -- for fairness' sake they need to consume more, the way we do.
Using this technology, we showed that genome wide allelic imbalance patterns are different in tumors from non-smokers when compared to that of smokers.
The present work represents the first comparative study of genome wide allelic imbalance between EGFR mutated lung ADC and KRAS mutated ADC.
We used Affymetrix GeneChip® Mapping 10 K and 50 K SNP microarrays to evaluate genome wide chromosomal imbalance (loss-of-heterozygosity and DNA copy number changes) in 48 representative tumors.
Similar sponsorship systems exist across the Middle East, creating a region-wide power imbalance between employers and migrants that often leads to migrant abuse, or even death.
France joined later but at a lower rate; high inflation had made the pre-war rate unrealistic.This set the stage for a period of wide trade imbalances and for the Depression that followed.
When the system is subjected to an unexpected disturbance that causes a significant system-wide power imbalance, the reduced system inertia can cause a larger and faster ROCOF and frequency nadir, which are two critical variables to set the relays for maintaining frequency stability [10, 11, 12].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com