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A chromosome wide examination of X inactivation, using RNA-seq, was recently undertaken in grey short-tailed opossum (Monodelphis domestica) brain and extraembryonic tissues.
A genome wide examination of this aggressive tumour variant with the more comprehensive Affymetrix chip currently available (i.e., HG-U133 plus 2.0 covering 47 000 human transcripts and variants) has provided evidence that G3-ECC genetic fingerprints can be clearly distinguished from those of NE.
There have been no exome-wide examinations of genes mutated in seminomas or of overall rates of nonsilent somatic mutations in these tumors.
Studies of specific candidate genes as well as genome-wide examinations of DNA methylation have demonstrated clear relationships to infant birthweight, supporting the role of DNA methylation in mediating these risks [ 7, 8].
Genome-wide examinations of nucleosome positioning in model organisms [ 1– 10], as well as in humans [ 11– 16], have uncovered a variety of associations among nucleosome positioning and spacing probabilities, underlying DNA sequence composition, histone modification, TSS distribution, gene expression, and rates of mutagenesis and repair in various tissue types in different organisms.
More rigorous analyses of each of the extended loci will be needed to establish transferability across ancestries, but these examples of locus-wide examinations provide preliminary insights to suggest that the transferability of obesity-susceptibility loci across ancestries might be more extensive than is suggested by SNP-to-SNP comparisons.
But as I pointed out above, a wider examination of econometric models has neither candidate decisively ahead.
The plan is for a draft bill to be produced for wider examination after the November 23 Queen's Speech.
— Maria Newman BBC: The horse meat scandal may be prompting a wider examination of meat in the European Union.
Black studies calls for a much wider examination of the problem of a neocolonial economic order that destroys poorer countries to the point where people are willing to risk their children's lives on makeshift boats.
BBC executives should consider the future of 6 Music as part of a wider examination of how best to improve the performance of its network of digital radio stations.
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Justyna Jupowicz-Kozak
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