However, there is limited evidence demonstrating their system-wide effectiveness.
In order to increase community-wide effectiveness of antimalarial treatment, the popularity of home-management and the quality of treatment obtained from commercial shops need to be better addressed.
The development and pilot process is summarised in Figure 1.The wider effectiveness and acceptability of the intervention is currently being tested in the OPTI-SCRIPT study (OPTImizing PreSCRIbing for Older People in Primary Care, a clusTer randomized controlled trial) which is described in detail elsewhere [ 18].
Other models assess country-wide intervention effectiveness (16, 31) but do not explicitly parse the specific intervention strategies that are effective in particular settings.
This realization has driven the renewal of the health systems strengthening (HSS) concept, which is now prominent in the wider aid effectiveness agenda [ 1, 5- 8].
One use of such an exercise is to locate the relative position of these interventions within a wider cost effectiveness framework in the healthcare sector, as attempted in the final article of this series.
We hope that such analyses will (i) explain past antivenom failures described following snakebite by members of this medically important genus [ 18, 22- 24] and (ii) identify the venom toxin mix required to generate an antivenom with continent-wide clinical effectiveness against Echis envenoming.
Furthermore, the project will extend our knowledge of biomarker-driven prognostication to encompass the wider cost-effectiveness implications using a simulation approach.
Using its wide range of effectiveness against bacteria, silver sulfadiazine has been widely used in burn wound-care.
The wide spread of effectiveness results shown in the scatter plot illustrates that the results are associated with considerable uncertainty surrounding key effectiveness and outcome parameters.
"There seems to be a wide range of effectiveness over all of the stability-control systems," said Rae Tyson, a spokesman for the federal agency.
