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"wide difference" is a correct and usable phrase in written English.
It is used to describe a significant or substantial difference between two things. Example: "There is a wide difference between their approaches to solving the problem."
Exact(60)
On the question of autonomy there was wide difference of opinion among different cadres of medical and nursing staff.
While these studies may represent extreme ends of the spectrum in accessing care, they illustrate the wide difference in healthcare-seeking behaviours in different settings.
There was a wide difference in outcome for patients admitted to different ICU's by using risk adjustment methods.
The wide difference between the reported prevalences might be due to the different methods of analysis.
A wide difference was found in the total extractable DNA as derived from different extraction protocols.
Or, play different types of music throughout the evening if your guests have a wide difference in music tastes.
The backdrop of the current battle is the wide difference between the adversaries.
obviously there is a wide difference between the scope of the two sections.
The data has shown a bell curve a wide difference in survival, depending on which center you get care from.
The wide difference between advocacy and incitement, between preparation and attempt, between assembling and conspiracy, must be borne in mind.
And there is a wide difference between declining the alliance of an inland and of a maritime power.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com