Global health initiatives are faced with human resources issues as a major, system-wide constraint.
Thus, this kind of selection, called Mistranslation-Induced protein Misfolding (MIM), is a genome-wide constraint for coding sequence evolution in both prokaryotic and eukaryotic domains.
The environmental movement comprises thousands of groups worldwide that have been working for years, quite successfully in many cases, to achieve serious, economy-wide constraints on greenhouse-gas emissions.
Our model includes three system-wide constraints.
In a broader sense, it was expected that the policy would help address some of the wider constraints facing livestock development in Nigeria at the time, such as disease control and market supply (Ingawa et al. [1989]).
That's because the unique network synergies of the combined network far exceed the sum of its parts, and generate the functional equivalent of new spectrum, which is the best means of addressing the macro-level, system-wide constraints confronting AT&T".
Hollande has little power to alter these wider constraints.
Strong correlations between the AT content of rRNA genes (rns and rnl) and the AT content of protein-coding genes among 24 cnidarian genomes imply that base composition is mainly determined by mt genome-wide constraints.
These constraints lead to a set of design guidelines, which maintain the wide scale constraints under increasing detail.
Category theory provides a way of stating wide scale constraints.
Cumbria County Council said the proposed reduction in funding should be considered in the context of wider budget constraint.
