Here we present FusoBase, an online database providing access to genome-wide annotated sequences of Fusobacterium strains as well as bioinformatics tools, to support the expanding scientific community.
F. succinogenes possesses genes with a wide range of annotated hemicellulolytic activites including a large number of xylanases, arabinoxylanases, mannanases, curdlanases (β-1,3 glucanases), licheninases (β -1,4 glucanases), and xyloglucanases; these enzymes come from a range of GH families including GH10, GH11, GH18, and GH26 (Table 3).
One genome-wide bioinformatics study annotated more than 45,000 conserved miR binding sites in the 3' UTR of 60% of human genes [ 22].
Genome wide association studies annotating the 72 Type 2 Diabetes (T2D) SNPs identified in the Persian genome sequenced in this study.
A wide range of proteins annotated as part of cytokines, chemokines and interleukins pathways were observed.
Our biocuration experience within the eagle-i project was unique due to the ontology-driven technology, the diverse and geographically distributed Curation team, the separation between data collection and curation, and the wide spectrum of resources annotated.
To illustrate NTLs and TIARs on a wider scale we have annotated the complete sequence of human chromosome 21 with DDM.
We selected the mouse as the homologous species to humans due to the wider coverage of the annotated genes.
Many are currently being used by a variety of scientific resources to annotate a wide range of biological and biomedical data.
This is opposed to the commonly followed strategy in which the most significant SNPs from a genome-wide association analysis are annotated to search for possible biological pathways associated with the trait.
Since transcription start sites have not been annotated genome-wide and the majority of annotated transcription start sites in the compact P. falciparum genome are located within 500 bp of the translation start site, we used the 500 base pair region directly upstream of the translation start codon to compute nucleosome characteristics of promoter regions.
