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Defects of mitochondrial protein synthesis lead to a more wide and severe phenotype than isolated POI.
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The mutant mice are slightly smaller in body size than their wild type littermates and exhibit craniofacial abnormalities associated with craniosynostosis including a dome-shaped skull, wide set and proptotic eyes, and severe midface hypoplasia.
Long-term climate projections, Dr. Worrall and other scientists say, all point to more curveballs ahead — wider, more severe fluctuations and variations of hot, dry, wet and cold.
For example, the full-length 10-item physical functioning scale of the SF-36 allows for the sampling of a wider range of severe and minor physical limitations and may provide for a better representation of the levels and types of physical limitations in this population [ 18].
However, regarding the differences in mortality rates covering different postoperative time spans and the wide range of "severe" postoperative complications reported in the (mainly retrospective) literature after surgery with or without radiation therapy, further clarification is needed by standardized reporting of toxicity data from prospective trials.
Our definitions of nipple damage are as follows: mild 1 or 2 mm wide; moderate 3 9 mm wide; severe: greater than 10 mm wide and / or yellow colour visible in crack.
Ogden syndrome is a genetic disorder with a wide variety of severe phenotypes and ultimately leads to mortality during infancy in males.
It accounts for up to 1% of hospitalized patients and may happen in a wide variety of severe medical conditions, including sepsis, trauma, obstetrical complications, transfusion and toxic reactions, rheumatologic illnesses, vascular abnormalities and also in neoplasms [ 1].
Thus, being poor means you have a far better chance of unnecessarily being prescribed the kind of psychiatric drugs that make you overweight and may cause a wide array of severe physical problems.
The histopathologic finding of patient from this outbreak showed a wide variety of severe pathologic tissue changes and 7 of 12 (58.3%) eyes underwent encucleation or evisceration [ 9].
Alemtuzumab is a potent immunosuppressive therapy that can lead to a wide variety of severe infectious complications, especially viral and bacterial infections [ 15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com