Sentence examples for wide activation from inspiring English sources

Although our data do not show a wide activation of senescence-related genes, several senescence transcription factors were clearly activated with an expression trend correlated to glyoxylate cycle and to many stress response genes, indicating the activation of early heat stress-induced senescence in Cappelli.

TBI induced a wide activation of pathways that regulate cell cycle control and DNA damage repair [ 34, 35].

For Heuninckx et al. [ 11], such a wide activation extending to associative areas of the cortex reflected the need for older adults to exert greater cognitive control over on-going actions to maintain performance at the desired level [see also [ 15]].

The analysis by IPA of activation of immune response pathways in jejunum, ileum and colon showed that TBI induced a wide activation of these pathways in all three intestinal segments at day 4, with significant suppression of the activated pathways at days 7 and 12 (Fig.  5).

Genome-wide activation of suppressed heterochromatic elements is a suggested outcome of regulatory instability (genomic shock, [8]) that characterizes allopolyploids [1], [2].

Together, these data suggest that cryoinjury results in an organ-wide activation of a developmental gene program and induction of cell proliferation in the epicardium.

The system-wide activation of CD4+ T cells results in an increased number of infected cells and high viral reproduction that leads to viral peaks observed in the primary stages of the infection.

Thus, the elevation of NFKBIZ in peripheral cells derived from autistic probands may be a reflection of a systems-wide activation of the innate immune system in autism, providing strong support for the use of LCL as a surrogate model to examine gene dysregulation in ASD.

Model-based analyses indicated that Y992F mutation caused rapid EGFR degradation through the up-regulation of EGFR ubiquitination and aberrant temporal activation of ERK1 by network-wide activation of tyrosine-phosphorylation; this suggests that pY992 strengthens and attenuates phosphotyrosine singling by distinct regulatory mechanisms.

The dedifferentiation and proliferation of pre-existing cardiomyocytes during zebrafish heart regeneration is preceded by rapid and organ-wide activation of the endocardium and epicardium (Kikuchi et al., 2011; Lepilina et al., 2006).

Remarkably, there is evidence that a binding site for RA receptor gamma in the Hoxa1 upstream enhancer is a key player in cluster-wide activation of Hoxb genes [ 46].