While this approach is still subject to the difficulties caused by correlated responses it allows the identification of groups of co-regulated genes whose regulation is likely to be adaptive.
In addition, we validated here a novel cell cycle-regulated protein (ARHGAP11A), whose regulation is mediated by targeted degradation by the APC/C.
Another class of E3 ligases, the HECT NEDD4 family [ 22], whose regulation has been extensively studied, also regulates endocytosis and sorting of numerous signaling receptors [ 3, 5- 7].
To verify the usefulness of the processed expression data for extracting transcriptional regulators, we initially interrogated the datasets for two pathways whose regulation is already well understood.
The effect would be to diminish the authority of the Federal Reserve, whose regulation of banks has been criticized for failing to head off the problems.
That is 22 points for the Rangers out of a possible 28, all in games against opponents whose regulation record stood no better than two games over.500.
Sleep is an essential and evolutionarily conserved behavioral state whose regulation remains poorly understood.
The VPI is 41.2-kb in size and encodes 29 potential proteins, several of which have no known function and whose regulation is not well understood.
Congress is hesitant because members draw campaign contributions from those whose regulation they review and fund, Bloomberg said, describing this as pay-to-play or something worse..
The apparent shared genetic influence of energy intake and expenditure whose regulation resides in similar central nervous system pathways, particularly in the hypothalamus and dopaminergic pathway, is noteworthy, supports our hypothesis, and merits further investigation.
In fact, biodegradation of pollutants relies on integrated activities of enzymes, cells, and microorganisms communities, whose regulation and kinetics are highly specific, though also greatly variable in space and time.
