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Such a model greatly simplifies the degeneracy of binding motifs, and therefore we expect to miss CRMs whose motifs exhibit low information content.
Expression profiles of POU factors as well as of HMG and Forkhead factors whose motifs were also identified through promoter analysis led us to propose Oct4 (Pou5f1), Tcf7, Lef1, and Foxc1 as regulators of a transcriptional network potentially under control of Wnt signaling.
Column 5 lists Table 14 entries whose motifs are very similar (max. 1 mismatch).
Although some of these unassigned motifs may be artifacts, others may simply correspond to TFs whose motifs are not contained in the two motif databases we searched.
The large numbers of motifs discovered by DREME that can be reliably assigned to TFs suggests that unassigned motifs may represent binding by other TFs whose motifs are not yet known.
Many ETS factors are expressed in embryonic hearts (Schachterle et al., 2011), and we selected ternary complex factors ELK1 and ELK4/SAP-1/TCF-1, whoccurredfs occurred in 26% of C-set peaks, for further analysis.
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From the tower they unfurl a red flag whose motif resembles the German eagle.
The lovers' tiff takes place in Peter McKintosh's appropriately claustrophobic wallpapered drawing room, whose motif of block-printed red roses with blue stems matches the chintz upholstery.
Alexis Mabille, whose motif was once a bow tie, had exchanged that for a new symbol: lacing up the leg of tight pants.
Illustration by Tasha Lewis In the chapter called "Sirens," whose motif is music, she recorded herself reading a sentence from the chapter, then cut a shape based on the sound wave of her voice out of a sheet of music.
First, a high background activity was observed in control assays (Figure 4), the origin of which is uncertain Secondly, in yeast cells, the BM2wt reporter mRNA, whose motif 1 is not fully complementary to the helix 26 target, showed an efficiency of termination-reinitiation only two-fold lower than the BM2yeast mRNA.
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