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The transcriptome, i.e. the whole set of RNA transcripts in a cell, is generally conceived as a system whose major function is to pass information encoded in the genome sequence to the realm of phenotypes that underlie physiological and pathological traits.
Hsp90 is a homodimeric ATPase whose major function is to assist in the late stage folding of metastable proteins (Nathan et al. 1997).
Upon most occasions, GRP78 is regarded as an endoplasmic reticulum chaperone, whose major function is to fold and process the unfolded or malfolded proteins [ 6].
TP53 is a universal tumour suppressor whose major function is to control the stability of genome in response to various forms of genotoxic stress.
Integrins belong to a family of heterodimer transmembrane receptors whose major function is to mediate adhesion and migration through extracellular matrix components [ 1, 2].
Among them, two pathways, ubiquitin-mediated proteolysis and protein processing in the endoplasmic reticulum, dominated the composite FFLs, whose major function is folding, sorting, and degradation and these are key mechanism in CF [ 67].
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Yingjin Wei et al. [14] point out that binder was an important component for battery electrodes whose major function was to act as an effective dispersion agent to connect the electrode species together and then steadily adhere them to the current collectors.
Constituents of the preocular fluid, whose major functions are physical, chemical, and antimicrobial protection, ocular mucins are produced by the surface epithelia, specialized goblet cells of the conjunctiva and by the lacrimal gland.
Functional analysis revealed that ubiquitin-mediated proteolysis and protein processing in the endoplasmic reticulum dominate the composite FFLs, whose major functions are folding, sorting, and degradation.
Its major function is to eliminate developing T-cells (thymoctyes) whose antigen receptor can bind self antigens and have the potential to cause autoimmune disease [ 1, 2].
Reinforcing this idea is the finding that vitamin E whose major function is to protect the polyunsaturated membrane lipids against free radical attack appears to be more effective against 4HPR-induced apoptosis than other antioxidants tested.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com