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Analysis of 3SEQ data from both frozen tissue and FFPET revealed several related cancer-associated pathways (prostate cancer, VEGF signalling, acute myeloid leukemia) containing a number of genes known to be important in carcinogenesis (AKT2, IGF1, BAD, PIK3R1, CCND1, PML, RARA), whose concerted role in SFT has not previously been characterized.
The highly parallelized nature with which such libraries can be generated also has the potential to expand directed protein evolution from single protein targets to protein networks whose concerted activities are required for the biological function of interest.
In some cases, these factors all converge on the promoter of a gene, such as FLO11, whose expression is required for pseudohyphal growth but more often these factors regulate distinct but overlapping suites of genes whose concerted action orchestrates the filamentous program.
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The continuing investigation into the genetic basis of cancer has revealed a number of genes whose individual or concerted actions, when mutated, result in oncogenesis.
The concept of pre-XDR TB is important for public health purposes, to allow the community to assess how many XDR TB cases are likely to emerge and to make concerted efforts to treat the individuals whose disease is caused by a pre-XDR strain of M. tuberculosis.
The results found for the nrITS region are comparable but more complicated than those of the single copy genes LEAFY and cGAPDH, because nrITS is part of a gene family, large tandem repeats of ribosomal DNA loci, whose copies are normally homogenized by mechanisms of concerted evolution [ 37].
François de Salignac de La Mothe-Fénelon, (born Aug. 6, 1651, Château de Fénelon, Périgord, Fr. died Jan . 7 , 1715Cambrai) French archbishop, theologian, and man of letters whose liberal views on politics and education and whose involvement in a controversy over the nature of mystical prayer caused concerted opposition from church and state.
For 2 decades, the temperature limit for known organisms has hovered around 110°C, despite concerted efforts by scientists to find a record-breaking bug whose molecular machinery could stand up to more heat.
After decades of inattention, concerted efforts to revitalize the cemetery began in 1999, by groups including the Prospect Cemetery Association, composed of people whose forebears are buried there.
Obama and Gordon Brown urge concerted economic action.
Surprisingly, the fine words prompted concerted action.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com