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This exon is flanked by long (∼15 kb) inverted sequence whose complementarity is required for circularization (Dubin et al., 1995).
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Analyses of anticodons expected for antisense tRNAs also suggests translational activity by antisense tRNAs: genomes avoid sense tRNAs whose anticodons define by complementarity antisense anticodons that match stop (terminator) codons, and hence would form, if transcribed and processed, antiterminator (termination suppressor) tRNAs [ 45].
Creation of a functional spatial entity, whose development perspective is based on complementarity and synergies among both individual spatial entities and productive activities.
We used the concept of hydropathic complementarity to search for sequences whose amino acid sidechains display a reciprocal pattern of hydropathicity to those of the deletion junction of EGFRvIII.
However, we argue that flow heterogeneity generates a small but relevant beta diversity component (at the meter-scale), when biofilms differentiate into functionally non-redundant local communities whose diversified metabolic capabilities may induce regional complementarity [54] along the bedforms.
Importantly, one of the genes was integrin α5 (ITG α5), whose 3′-UTR sequence had a perfect complementarity with the seed sequence of miR-205.
My use of Jin Shin Jyutsu, a knowledge system whose roots are several thousand years old, draws attention to complementarity as a guiding tenet rather than what is true or what is best.
One potential gene target of miR-152 based on sequence complementarity is the Janus kinase family member, Jak1, whose corresponding protein product is highly involved in cytokine-mediated signaling.
Contrary to nucleic acids, whose molecules can be recognized (and separated) on the ground of their complementarity, proteins do not possess such a unique system for specific recognition of individual protein types.
Scanning of the SHIP1 3′-untranslated region (3′-UTR) revealed perfect sequence complementarity with the seed sequence of miR-155 (Fig 1C), an onco-miR whose ectopic expression gives rise to B cell malignancies (Costinean et al, 2006), but whose cellular targets have remained elusive.
Further analysis could be made in terms of the complementarity of species assemblages and their relationship to ecological systems and levels of protection, whose results could further guide priorities.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com