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It is possible, therefore, that apparently genetic diseases whose causative genes cannot be located really are heritable, but that the genes which cause them are bacterial.This is of more than merely intellectual interest.
Similar to all novel point mutations whose causative nature is not supported by a genetic linkage study, the question arises whether mutation T188K is truly pathogenic and not merely a polymorphism accidentally occurring in cases of sCJD.
MMS have been described in several chromosomal disorders and Mendelian diseases some of whose causative genes have already been identified.
b Number of patients/total number of patients whose causative pathogens and antibiotic sensitivity test results are known (percentages).
a Number of patients/total number of patients whose causative pathogens were identified in each pneumonia severity index class (percentages).
As described above, we isolated 115 independent mutant alleles whose causative mutations covered 20 out of 22 GPI-anchor pathway essential genes.
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Children or adults who have neither signs nor symptoms of infection, but from whose scalps causative fungi can be grown, are described as "carriers".
The only known causative gene is Lamp2 whose mutations cause Danon disease.
Human Bocavirus (HBoV) is a newly discovered parvovirus whose role as a causative agent of respiratory disease remains unclear.
Bottom panel: a sketch showing the causative bodies whose characteristic parameters are shown in the top panel.
Poly-glutamine (polyQ) diseases are neurodegenerative disorders characterised by expanded CAG repeats in the causative genes whose proteins form inclusion bodies.
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