Exact(2)
Depot formulations were considered continuously over the whole dosing period.
Both regimens were found to result in a free drug concentration exceeding the MIC value for staphylococcal species of 8 μg/mL (taken from the literature) for the whole dosing interval, so therefore there was no benefit in a second dose.
Similar(58)
Of course, be careful to follow your doctor's directions: Using antibiotics for viral infections, or not taking the whole dose, promotes the development of drug-resistant bacteria.
In the ToGA study the planned dose was the whole dose of an actual administered cycle.
The small nasal volume administered ensures that absorption of the whole dose occurs transmucosally in the nares.
CONPs were injected via the vena caudalis three times, achieving a whole dose of 6 mg/kg.
Possible future developments of our protocol include the evaluation of the efficacy of dose rounding other than 5% of the whole dose.
The mean of the whole dose series (mean log scale = 4.12) was subtracted from every dose value to center the data.
Thus, we were able not only to increase the weekly dose by 17% in the experimental arm, but also to deliver the whole dose intravenously.
If the mean of the whole dose series was not subtracted, this comparison would have been the difference between cysts and trophozoites at a log dose of zero (dose of 1).
In the AVAGAST study the planned dose of cisplatin was the entire dose of all six cycles, and that of capecitabine was the whole dose of an actual administered cycle.
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