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This staging period is generally chosen to closely monitor the macroscopic changes which often only develop slowly: For example in 35 patients with hepatocellular carcinoma treated with SIRT, WHO responses were only seen in 3 patients after 1 month and increased to 13 patients after half a year [ 49].
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Hence, either the GCIG CA125 criteria overestimate the WHO response rate by a factor 1.46 or, alternatively, WHO response criteria underestimate a GCIG CA125 response by a factor 0.68.
Negin describes the current WHO response to an outbreak of drug-resistant tuberculosis in Papua New Guinea as having a "similar pattern" to the Ebola catastrophe.
Meanwhile, Prime Minister David Cameron criticised the World Health Organization's (WHO) response to Ebola.
Conclusion: For MPM bidimensional WHO response evaluation cannot automatically be replaced by RECIST because MPM has a non-spherical growth pattern.
WHO response criteria were used.
Tumour response was assessed according to WHO response criteria.
MDA response criteria correlated better than WHO response criteria with clinical response assessment.
In patients with measurable or evaluable disease, response was evaluated using WHO response criteria (WHO, 1979).
Alternatively, the WHO response criteria underestimated a CA125 response by a factor 0.68.
WHO response criteria were used to evaluate response in this study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com