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Marked by a simple white plaque, the wooden door stays firmly closed to the public.
"If we find amyloids, a white plaque deposited on the brain, we'll know it was an ancient disease as well as modern," Dr. Brier said.
Oral leukoplakia (OL), which is the most common among these lesions, is defined by the World Health Organization as "a white plaque of questionable risk having excluded known diseases or disorders that carry no increased risk for cancer".
In this work, we employed a mouse model of oropharyngeal candidiasis, in which the white plaque lesions were faithfully reproduced, to systematically characterize the composition of mucosal biofilms in situ.
It has been hypothesized that biofilm growth of this organism on mucosal surfaces is responsible for the white plaque oral lesions, which are highly diagnostic of pseudomembranous candidiasis [5].
These included one colony of D. strigosa infected with white band disease at SR2 and two colonies of M. faveolata with one exhibiting symptoms of white plaque and the other of black band at CV1.
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It grows in smooth white plaques engraved with dark lines, like hieroglyphs, from which it takes its name.
Herpes simplex virus causes an infectious, painful gingivostomatitis, characterized by the development of white plaques and vesicles in the mouth.
After incubation 3h at 37°C, white plaques were seen only where PAI-1 inhibited uPA activity.
Clinically this infection presents as white plaques on the oral mucosa, which can be removed by gentle rubbing [6].
However, bacterial-Candida co-existence within the oral white plaques in humans or animals has never been demonstrated in situ.
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