Sentence examples for whilst minimally from inspiring English sources
shR-P16, which previously demonstrated high efficiency target selection in the full-length hemizygous assay, again showed high mutation-specific selectivity in the heterozygous disease model system, efficiently knocking down the mutant transcript to 7% of control levels (p<0.05) whilst minimally affecting the wild-type (74% of the control levels; Figure 4).
Whilst minimally invasive probes are necessary to analyse chromatin structure and the distribution of supercoiling in vivo.
Minimally invasive and percutaneous surgery for the Achilles tendon rupture aims to provide a stable repair, allowing early weight-bearing and movement, whilst minimizing the risks of wound breakdown or infection (Del Buono et al., 2014; Khan & Carey Smith, 2010; McMahon et al., 2011; Yang et al., 2017) (Figs. 1a.
Van der Veen et al. demonstrated that a dose of 20 mg/kg/day of GW610742 in mice gave an average plasma concentration of 1 μM; given that the specificity of GW610742 for PPARδ is 28 nM compared to 8,900 nM for PPARα and >10,000 nM for PPARγ, then the current study will saturate the PPARδ receptor whilst only minimally activating the other PPAR isotypes [ 27].
Whilst the synovial membrane is accessible using minimally invasive techniques, which can be applied even in the earliest phases of the disease [ 34], histologic verification of the bone edema seen on MRI is virtually impossible in early disease because of difficulties in obtaining appropriate biopsy tissue.
The most populated categories show a significant reduction in the intensity in one of the samples whilst the intensity in the other sample is minimally reduced.
Whilst 47% opted for open surgical procedures, one surgeon undertook minimally invasive surgery only and 51% performed both open and minimally invasive operations.
Sutureless valves were designed in an attempt to simplify the aortic valve replacement procedure and reduce extracorporeal circuit time, whilst allowing complete excision of the calcified native valve using a minimally invasive approach.
The aim of PATHOS is to determine whether reducing the intensity of adjuvant treatment after minimally invasive transoral surgery in this favourable prognosis disease will result in better long-term swallowing function whilst maintaining excellent disease-specific survival outcomes.
