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While we designed this experiment to test RVG-9r LSPC-mediated PrP siRNA delivery to PrPC-expressing neurons, we also observed a significant decrease in PrPC expression on CNS cells after just 24 hours post treatment.
While we designed Introduction to Scientific Thinking for future biology majors, the approach could be easily adapted to other STEM domains.
For hTERT α+β+ we used the same primers and probe and for mammaglobin the same primers as previously reported [ 36, 37], while we designed novel hydrolysis probe and primers for TWIST1 and a novel hydrolysis probe for Mammaglobin (Table 1).
While we designed the intervention activities to be conducted within the constraints of current staff numbers, it is possible that the planning and coordination of activities performed by the intervention team, as part of the modelling exercise, could not be sustained in their absence.
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While we design all of our tasks to be fun and engaging, they still require smarts and skills, and we figured it would be cool of us to throw in some just-for-smiles tasks.
The high degree of symmetries of the AC-LEEM are utilized while we design the electron optics of the ultrafast spin-polarized electron source, so as to minimize the deleterious effect of time broadening, while maintaining full control of electron spin.
And while we design to be decided and explicit in all our positions, we shall at the same time seek to be temperate and measured in all our language.
In order to increase the efficacy while minimising toxicity, we designed a new chemotherapy protocol in which UFT/LV is alternately combined with L-HOP and CPT-11.
While the activities we designed varied somewhat in their complexity, all activities required students to make an explanation of a biological phenomenon based on evidence, either experimental results or models that students developed to support their thinking.
Because there has been an increased focus recently on minimizing sedation to improve MV outcomes, and because patients with AOD may require a different approach to sedation while on MV, we designed a study to determine the prevalence of AOD and sedation needs among our medical ICU patients undergoing MV.
Considering the need to strengthen learners' Representational Competence and support their cognitive load demands while translating among MERs, we designed an additional interaction in dynamically linked MERs.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com