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While interruption of coverage was sometimes seen near the 3' end of certain tRNAs, it is clear that the "tRNA punctuation" mode of transcript processing described in mitochondria of animals and to some extent yeast and red algae, relying on precise excision of the tRNAs from the primary transcript [ 20– 22], is not predominant in the mitochondrion of L. incisa.
Importantly, however, antibody levels remained low under combined therapy with azathioprine and prednisolone over an observation period of up to 500 days with no further clinical attacks, while interruption of azathioprine resulted in clinical relapse and an increase of antibody levels within 1 6 months.
The interrupted amino acid residues are different in patterns d and e, e.g. interruption of Gln in pattern d while interruption of Arg in pattern e. Pattern f does not have intron in the basic and hinge regions and contains 16 SlbZIPs (Fig. 4 and Additional file 9: Figure S5).
The latter observation indicates that cell cell contact per se controls the expression of numerous genes in BM cells, while interruption of the contact relationships relieves cell to cell regulation and permits full expression of the 'default' genetic program inherent to each individual cell.
Thus, while interruption of the 3′ end of Matr3 by the gene trap insertion reduces wild-type transcripts in Matr3GT-ex13 heterozygotes, this is accompanied by the expression of a fusion transcript that may encode a functional or partly functional Matrin 3-β-Geo fusion protein.
Similar(55)
Yet while interruptions are annoying, Mark's study also revealed their flip side: they are often crucial to office work.
Communication delays contribute to work disorganization when a worker is unable to move forward with a task due to insufficient information, while interruptions derail the flow of activities directed toward the accomplishment of a task.
In terms of nutrition, some people who were judged to need help eating were not getting it, while interruptions meant that not all meals were being finished by patients.
While interruptions were the focus of all studies, only four provided a definition and these varied substantially.
In the case of interruptions it seems that a high work unit averaged level was associated with higher levels of depressive symptoms, while interruptions at the individual level were associated with lower levels of depressive symptoms.
While interruptions in medication drug use commonly occur due to financial concerns or side effects, it is less likely these factors played a role given the availability of generic medications with modest copayments and that most patients eventually restarted their prior urate-lowering medication.
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