Suggestions(2)
Exact(5)
While immunity induced by prior infection offered significant protection even in the absence of complement or FcγRs, vaccination-induced protection required both complement and FcγRs.
BPZE1-induced cross-protection against B. parapertussis is thus essentially T-cell mediated, while immunity induced by B. parapertussis infection elicits both protective B and T cells responses.
For this reason, while immunity contributes to the control of M. tuberculosis, immunity can, at the same time, frustrate the ability of drugs to eradicate it (15 – 15).
Focussing on groups of genes in functional categories, we find that transcription factors contain a significant excess of nonsynonymous base-positions that are conserved in other mammals but changed in human, while immunity related genes harbour mutations at base-positions that evolve rapidly in all mammals including humans due to strong preference for advantageous alleles.
Notably, mice deficient in IL-25 (IL-17BR−/−) or IL-33 (T1/ST2) receptors mount poor type 2 responses and are more susceptible to infection with Nippostrongylus brasiliensis, while immunity can be restored to these animals by transfer of ILCs acting in an IL-13-dependent manner [ 13 ].
Similar(53)
This explains why immunization with B7.1 expressing CMT.64 cells induced a high level of anti-CMT.64-tumor immunity while immunization with B7.1-negative CMT.64 cells provided significantly less immunity.
While immunity-related genes comprised only 6.1% (247/4047) of all genes expressed in hemocytes, 10.9% (105/959) of differentially regulated transcripts belonged to this functional class.
For example, in hemocytes from mosquitoes challenged with E. coli, the cytoskeletal/structural class was significantly over-represented in the group of differentially regulated genes compared to other functional classes (χ2 = 8.32, P = 0.0039), while immunity-related genes were not.
Human immunosenescence is accompanied by a deterioration of B and T cell-mediated adaptive immune responses, while innate immunity is rather preserved or even upregulated [ 51].
In the asymptomatic form of pcm, T-helper type 1 (Th1) specific immune response occurs, while Th2 immunity is associated with severe disease [16], [17], [18].
The evolution of the innate immune system dates back to the first single cell organisms, while adaptive immunity evolved not before the appearance of the jawed cartilaginous fish around 500 million years ago [ 12].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com