Sentence examples for while activator from inspiring English sources

Under apoptotic conditions, pro-death sensitizer BH3-only proteins bind and inhibit pro-survival Bcl2 members, while activator BH3-only proteins directly bind and activate Bax and Bak [ 2], triggering mitochondrial outer membrane permeabilization (MOMP).

Estrogen response element activity is repressed by both ER-α and ER-β in the presence of tamoxifen, while activator protein 1 (AP-1) responsive elements are activated by both receptors in the presence of tamoxifen.

Following the standardized qualitative dynamical systems methodology (Mendoza and Xenarios, 2006), Equation (1) states that inhibitor functions are strong enough to change the state of the output gene from 1 to 0, while activator functions can change the state from 0 to 1 if and only if no inhibitor functions are acting on that gene.

Inhibition of SIRT1 could be useful for cancer treatment while activators can be useful for longevity and treating metabolic disorders.

PKA inhibitors reduced [Protein Kinase Inhibitor (PKI) – 56%; H89 – 54.5%] kemptide phosphorylation by Leishmania major promastigote lysates, while activators increased phosphorylation (8-CPT-cAMP – 88%; Sp-cAMPS-AM – 152%).

We show herein that the activation of a β-catenin-independent pathway, mediated by Wnt7a/Fzd9, strongly induce hsa-miR29b expression in NSCLC cells (Fig. 1), while activators of β-catenin-dependent pathway (Wnt3), in strong contrast, failed to stimulate hsa-miR29b expression.

Activated macro-phages secrete ferritin as well as plasminogen activator, while activated T and NK cells shed their IL-2 receptor, further contributing to the characteristic laboratory abnormalities of HLH.

While tissue plasminogen activator (tPA -activated plasmin has been suggestPA -activatedplasmindiated regulation of NMDA receptor function in a manner relevant for synaptic plasticity and behasiour [ 204, 205], NMDA receptor activity seems to beenecesuggested torombinduce1-induced neurodegenerative effects under pathological conditions such as ischemia or hemorrhage [ 206, 207].

For labeling of reporter antibody, Yb3+ was maintained as the sensitizer ion, while the activator ion was switched to Tm3+ in order to prepare NaYF4 30%Yb0.5%Tm UCNPs emitting blue color.

The results revealed that both the phospholipid-to-drug ratio and sonication time had a pronounced effect on particle size, while the phospholipid-to-drug ratio and hydration medium pH, showed a significant effect on drug entrapment efficiency, while edge activator concentration and sonication time showed a significant effect on diffusion steady-state flux.

While the Activator didn't really work – IGN  ​named it the third-worst controller, ever – it showed that Sega was willing to invest in hardware development that went beyond what other manufacturers were attempting.