Sentence examples for while abrogation from inspiring English sources

This is supported by siRNA experiments in which inhibition of PHD2 led to a normoxic activation of HIF while abrogation of PHD1 or PHD3 expression did not have this effect [9].

FGFR4 activation shifts BA production towards CDCA, while its abrogation leads to CA formation.

Excessive induction of IL-1 during high-fat feeding drives adipose tissue inflammation and IR while complete abrogation of IL-1 results in excessive weight gain with maturity that, when combined with a high-fat insult, results in advanced obesity and systemic IR.

While a complete abrogation of MLC can be beneficial in limiting tumor cell motility and hence invasion, partial inhibition using lower pharmacological doses can paradoxically increase tumor cell motility and invasion leading to devastating consequences.

While the precise mechanisms underlying abrogation of TGF-ß signaling remain to be fully delineated, we found that PPAR-γ blocked Smad-dependent transcriptional responses without interfering with Smad phosphorylation or nuclear accumulation.

Pretreatment of ShhMSCs with these inhibitors abrogated PKM with concurrent abrogation of iNOS and netrin-1.

The two processes are coevolutionarily interconnected: natural selection favors the evolution of characteristics that inhibit oncogenesis, while oncogenic selection favors their abrogation.

It demonstrated that miR-155 still efficiently inhibited luciferase activity after abrogation of the first seed while it had no inhibitory effect on the activity of MUT2 (Fig. 6B), indicating that only site 2 was functional.

Interestingly, the checkpoint activation profile was observed to be different during G2/M synchrony where a complete abrogation of Chk1 was observed while ATM and Chk2 activation was observed at 30 minutes post release from G2/M block in NEU drug.

While I agree that the upshot is an abrogation of constitutional protections, I don't credit Ferguson or St . Louis Countycops with the Machiavellian cunning required to intentionally silence journalists.

The goal of any therapeutic intervention is abrogation of pathogenic reactivity to autoantigens, while preserving full capacity to mount a normal immune response against foreign pathogens, with preservation/restoration of B-cell mass and function.