57, 58 Currently there are no available guidelines which suggest specific increases of BCR ABL transcripts that warrant a change in current therapy.
Our findings are also consistent with reports demonstrating coordinate regulation of the phosphatidylinositol 3-kinase related kinases (PIKK) kinase family members (includes ATM, ATR and DNA-PKcs) by mammalian Tel2, which suggest specific dependence for protein stability [ 30, 31].
These results are in keeping with models of cognitive aging, which suggest "specific" rather than general age-related mechanisms, under which changes to language reflect linguistic factors rather than reflecting a general cognitive resource limitation (e.g., Burke et al. 2000).
Tests conducted on well-water samples showed coliforms, enterococci, and Salmonella togba, which suggested specific fecal contamination.
ETB receptor binding in the rat HSN tumour was concentrated in small regions of intense binding (Bell et al, 1998), which suggested specific vascular localisation.
In addition, a previously performed Northern Blot study on the whole brain tissue found no difference between those two strains [ 41], which suggests specific distinction in distribution of those transcripts in the striatum.
Moreover, six genes were remarkably up-regulated under heat stress condition, i.e. ZmHsf-01, ZmHsf-03 and ZmHsf-23, and et al., which suggested specific roles for these genes in maize during heat stress.
Target genes were selected based on previous microarray data obtained from studies of larval offspring reared on an HS diet (Musselman et al., 2011), and also based on the body composition changes that were seen, which suggested specific metabolic pathways as potentially regulated.
Recent studies have shown associations among M. tuberculosis strains, geographic regions, and human populations, which suggest that specific strains of M. tuberculosis coevolved with human subpopulations (18 – 20 ).
Despite a high sequence similarity, the mouse P-gp1a and P-gp1b isoforms show distinct patterns of tissue distribution which suggest a specific role of the P-gp1b isoform in steroid transport.
Even when familial origin is suspected, such as in the case of bilateral presentation of PCC, pathological features which suggest a specific aetiology to the disease are desirable to differentiate VHL-related tumours from RET- and NF-1-related tumours (Koch et al, 2002).
