Moreover, in the Cln1 −/− mice, suppression of neurotrypsin activity by serpina1 inhibited the cleavage of agrin (a large proteoglycan), which substantially reduced the production of agrin‐22, essential for synaptic homeostasis.
The analytical model here, which includes vapor condensation on the tank walls, predicted total in-breathing requirements for mixtures of air saturated with vapors, which are substantially larger than those calculated using the procedures in the standards.
By contrast, for the negative binomial and gamma distributions, which have additional parameters which can reflect skewness, sample size calculations based on differences in means can be very conservative, giving larger numbers which substantially exceed the required power.
And the Russian army, which is substantially larger than Chechnya's entire population, has occupied the territory since 1999.
The Reporting Persons believe that the Issuer's patent portfolio, which is substantially larger than Nortel Networks' and includes numerous patents concerning 4G technologies, has significant value.
Many of its superstores, which are substantially larger, include full grocery stores, pharmacies, even beauty parlors and opticians.
However, a significant synergy effect was also observed in the combined processes, which was substantially larger than any single process.
The total effect of mood/anxiety disorder is 2.75 (OR = 15.7, p ≤ 0.001) which was substantially larger than the direct effect (OR = 0.93).
Vink and Yamazaki (2014) introduced a different critical Mach number (Macc), which is substantially larger than the first critical Mach number (Mcrit) of quasi-parallel shocks (Kennel et al. 1985) but similar to Mcrit of quasi-perpendicular shocks.
MFCs with the 50% wet-proofed cathode (2 DLs) had a CE of >84% (6.8 A/m2), which was substantially larger than that previously obtained using carbon cloth air-cathodes lacking separators.
