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A Ti(C,N TiN WC Co cermet material was subjected to a heat-treatment in nitrogen which substantially improved the plastic deformation resistance during cutting.
We modified the structure of hit compound 7 (human TRPV1 IC50 = 411 nM) and converted its pyrrolidino group to a (hydroxyethyl)methylamino group, which substantially improved inhibitory activity (15d; human TRPV1 IC50 = 33 nM).
Aging at 550 °C for 3 h introduced coherent 10 20 nm precipitates in the matrix, which substantially improved the shape memory and mechanical properties of the Ni50.3Ti29.7Hf20 crystals.
Later on, this product occupied the majority of domestic market share of Azithromycin with competitive price advantages, which substantially improved the access to the Chinese people.
However, Mexico's relatively unfavorable legal framework for petroleum exploration had discouraged exploratory activities until 2014, when a new hydrocarbons law was passed, which substantially improved the attractiveness of exploratory efforts in the country.
To address these problems, we have previously reported five stacks of C60/LiF CBL, which substantially improved the device efficiency and stability of PSCs due to its good electrical conductivity even though a very thick LiF was used [26].
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Wild and genetically engineered AChEs from Drosophila melanogaster (Dm) were chosen for their high sensitivity towards insecticides, which substantially improves the LOD compared with cholinesterases from other sources.
An efficient preconditioner for Krylov method solution of linear systems is proposed, which substantially improves the solution of Poisson equation for pressure correction.
The resultant rutile TiO2 hierarchical nanotubes show unique structural features (hierarchical, hollow) and a large surface area (180 m2 g−1), which substantially improve their electrochemical performance.
The method demonstrates an effective means for generating cyclically operated reactor and adsorber networks which substantially improve upon the production efficiency of an equivalent adiabatic steady-flow reactor, whilst adhering to user-specified bulk separation constraints.
To address it, the two major contributions of this paper include: (1) development of a new multi-fidelity surrogate-model-based optimization framework, which substantially improves reliability and efficiency of optimization compared to many existing methods, and (2) development of a data mining method to address the discrepancy between the low- and high-fidelity simulation models.
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