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miR-210 is the only miRNA so far identified which strongly responds to hypoxic stress in virtually all experimental systems in vivo and in vitro and in both normal and tumour cells under physiological hypoxic conditions [ 91].
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Although this may be expected for genes of clusters I, II, IV, and VI, which are expressed in a CbfA-dependent but perhaps CbfA-CTD-independent manner, it was surprising to find that CbfA-CTD also had no effects on cluster III and V genes in AX2 cells, which strongly responded to CbfA-CTD expression in JH.D cells (as shown in Figure 5).
Next we established a luciferase reporter containing 7 × sequential GLI-binding sites (Fig. 5b), which strongly responded against GLI2ΔN, a constitutive active form of GLI2 12 (Fig. 5c).
The regulatory sequences of controlling expression of transgenes in rice are available now, so as a result, the transgene can be either normally expressed or expressed in response to a specific stimulus or artificially (including induced anaerobic stress, through the use of promoters from genes which strongly respond to waterlogging).
In particular, their transcript abundance peaked at 4 or 8 hpt, except for VpCDPK9 (Fig. 9-b), which strongly and rapidly responded to the treatment from 0.5 to 12 hpt with MeJA and peaked at 0.5 hpt.
A correlation analysis found that 12 VdRLs were adjacent to Verticillium wilt resistance QTLs, which strongly suggested that these loci respond during Verticillium wilt resistance in cotton.
Natriuretic peptides are 'loading markers', which readily and strongly respond to ventricular stress, while galectin-3 levels is viewed as a marker of interstitial fibrosis, less responsive to (un- loading.
Several years ago, Professor Kanwisher and colleagues identified a part of the brain called the parahippocampal place area (PPA), which responds strongly to images of indoor and outdoor scenes depicting the layout of space, but does not respond at all to faces.
We used the well-characterized receptor dOR22a (Pelz et al. 2006; Galizia et al. 2010), which responds strongly to banana extract (Hallem and Carlson 2006), and an artificial banana-like odor blend (Jordán et al. 2001), which allowed us to dissect the contribution to the odor response of different components.
To compare with the published transcriptomic study on carbon starvation, we specially analyzed the expression profile of genes related to carbohydrate active enzymes (CAZymes), hydrolases (chitinase, glucanase, protease, and phosphatidase), transporter, and the formation of conidiophore, which responded strongly under carbon starvation.
Interestingly, the authors identified ORs which responded strongly to human derived odorants and may be involved in host recognition.
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