Currently, ATRA based treatment has become the standard care of the APL which significantly prolongs disease-free survival (DFS) and overall survival (OS) (Fenaux et al., 1994, Avvisati et al., 1996, De Botton et al., 1998, Estey et al., 1999, Estey et al., 2005, Hu et al., 2009, Shen et al., 2004).
The flowing solution of HTCC/GP under room temperature could gelate rapidly at body temperature, which significantly prolonged the H5N1 split antigen residence time in nasal cavity.
In the case of GC/MS, the derivatisation step was required, which significantly prolonged the total analysis time.
Neoadjuvant imatinib therapy can shrink the size of locally advanced GISTs and increase R0 resection rate, which significantly prolong the RFS and OS comparing with the inoperable patients or patients with palliative operation [ 19- 23].
Different studies appropriately using serum tumour markers within an intensive post-operative follow-up showed that in many relapsing patients clinical-instrumental diagnosis was anticipated and that this anticipation permitted an earlier treatment which significantly prolonged disease-free survival (DFS) and/or overall survival (OS) [ 5- 8].
Factors which significantly predicted prolonged aggregated LOS (upper quartile, >10 days) were the same as in the primary analysis (data not shown).
Very low birth weight (VLBW) infants frequently experience hospital-acquired infection (HAI) during prolonged hospitalization, which significantly contributes to their mortality and morbidity.
Therefore, contaminants in the bypassed areas may not be contacted by the amendments in the remedial fluid, which may significantly prolong remediation operations.
Many of these patients develop severe pneumonias within a few days, which may significantly prolong their recovery.
Additionally, phasic inhibition evoked by stimulation of the nucleus reticularis exhibited a spillover component mediated by δ-GABAARs, which was significantly prolonged in the presence of etomidate.
On the other hand, the velocity-related parameters (RSI, RWO and MTT) in treated group changed gradually and were significant at the end of third week (Additional file 1, Table S3), especially the parameter of MTT, which was significantly prolonged at the end of the third week in the treated tumors.
