Sentence examples for which requires domain from inspiring English sources

Biocuration is a complex task, which requires domain expertise and specific training.

In our work, we focus on another kind of severe defects, modeling defects, which require domain knowledge to detect and resolve.

However, the forms of such binary feature descriptors are predefined in the hand-crafted way, which requires strong domain knowledge to design them.

They ask for accurate MSA of related sequences with low residue identities which requires some domain expertise.

A prior study shows that the N-terminus of Dvl1 (K5, 20, 34, 46, 50, 60 and 69 on the DIX domain) is modified by K63-linked polyubiquitination, which requires DIX-domain mediated polymerization of Dvl [ 79].

With the exception of TLR3, which requires TIR-domain-containing adapter-inducing interferon-β, all TLRs can initiate downstream signals through myeloid differentiation factor 88 (MyD88), while TLR4 can independently engage both MyD88 and TIR-domain-containing adapter-inducing interferon-β [ 8].

The other mutant of Akt is the naturally occurring, transforming mutant Akt1-E17K, which requires the PH domain for plasma membrane recruitment.

This is reminiscent of the situation with typeable and non-typeable H. influenzae, where in most cases the aminoterminal IgV-like domain of CEACAM1 is necessary, but not sufficient for binding, which requires additional IgC2-domains [51].

In particular, the amino-terminal domain of CEACAM1 is necessary, but not sufficient for Opa protein-independent binding, which requires multiple extracellular domains of the human receptor in a cellular context.

These GDSE process life cycle topics are somewhat different than in software engineering because of two factors: first, the GDSE domain has special needs and priorities, and second, it is a young domain which requires more fundamental research in the area of requirements, development, and coding tools.

The modification or deletion of residues in the α-helical segment, however, can profoundly perturb the folding and integration of the β domain into the OM and/or the proteolytic release of the passenger domain, which requires precise alignment of the cleavage junction with key catalytic residues (Dautin et al., 2007; Ieva et al., 2008; Barnard et al., 2012).