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The different gene-expression profiles in mammary tumors caused by the STAT5Δ750 and STAT5ca variants, corroborated by the absence of a direct link to transgenic STAT5 expression, imply distinct metabolic consequences for their oncogenic role which probably initiate early in tumor development.
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Therefore, we hypothesized that metallic NP-induced OS can probably initiate necroptosis and pyroptosis, which might contribute to the neurotoxicity of NPs.
It'll be the violence of the police that will probably initiate that sort of response from people.
Modifications in the balance of sex hormones at menopause probably initiate changes in sebum physiology.
Once he's noticed you, he'll probably initiate a conversation or two.
On the other hand intramolecular folding of BPL initiated by bio-5'AMP may impart steric hindrance which probably restrains orientation of the adenylate towards the self-biotinable lysine.
The signals induced by a novel environmental stimulus probably initiated different cascades of gene interactions, which led to novel phenotypic variations due to standing genetic variations that were invisible under normal circumstances.
In vertebrates pair bonding probably initiated a qualitative shift from loose aggregations of individuals to complex negotiated relationships which are generalized to all social partners in only a few taxa, for example in anthropoid primates (Shultz & Dunbar 2007).
We identify slab break-off and asthenospheric upwelling in this region and suggest that this process probably initiated the thermal and material erosion of the tectosphere beneath the Eastern Block from the Paleoproterozoic, which was further intensified during the Mesozoic when a substantial part of the sub-continental mantle lithosphere was lost.
The precise nature of this stress is currently unclear, but it is probably initiated by increased expression of or gain-of-function mutations involving oncogenes (e.g., CCN1, KRAS, or MYC), which are known to be early events in tumorigenesis.
The TWC inflow was probably initiated by the opening of the southern strait and the migration of the Kuroshio water into the East China Sea, which almost coincided with the formation of the Okinawa Trough (Shinjo 1999).
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