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Cytokinin is added to the basic model by changing the threshold concentration of auxin below which outgrowth will occur, and strigolcatone is added by having an inhibitory effect at the base.
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Development of effective cancer therapies may be limited by intratumoral heterogeneity, which facilitates outgrowth and organ-specific dissemination of treatment resistant clones.
Pathogen recognition and capture triggers a cascade of signaling events that leads to DC maturation, which involves outgrowth of dendrites, increased expression of MHC class II and co-stimulatory molecules, secretion of cytokines such as IL-12 and migration into T cell areas of lymphoid organs to present peptide antigen to naïve T cells.
Common to many of Dick's short stories were settings in which the outgrowth of modernity is a world where that which is natural is in ruin, and what is artificial is reshaped through science into a fantastically high tech form.
To examine if selective and penetrant inhibition of the catalytic activity of Mps1 is lethal, UTR- and HCT-derived Mps1wt and Mps1as cells were treated with 23dMB-PP1 for 8 days after which colony outgrowth was scored.
By focusing on these early time points, in which tumor outgrowth and subsequent regression occurred, we hoped to better understand not only how effector T cell function differed within the tumor mass relative to distal lymphoid organs, but also to identify changes that occurred in each site as the anti-tumor response progressed.
At high doses this eventually causes host death, after which fungal outgrowth of the corpse occurs [ 21].
The organoid fraction results from small fragments of partly digested tissue, from which an outgrowth of cells is observed (Fig. 2a).
This negative relation between PDGF-A and PDGFR-α has been previously described in chicken embryos in which epicardial outgrowth was inhibited [ 6].
Electrophysiological tests on flies in which neurite outgrowth of the GF was blocked showed that the only pathway from the brain to TTMn is via the GF (Allen et al., 2000).
These data are in correspondence with a preclinical model of severe Gram-negative sepsis in which bacterial outgrowth did not differ between WT mice and heterozygous and homozygous FVL carriers [ 18].
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