In this context, we might speculate as to which mutations might restore the wild-type level of a missing element in a given mutant, for example.
It also facilitates axonal remodeling and neurite outgrowth, which might help to restore neuronal functions (reviewed by ).
Their study revealed a critical role of caspase-1−/− mice in sepsis by protecting splenic B-lymphocytes from apoptosis, which might in turn restore natural antibody production by the B cells, preventing host from bacterial predisposition.
Furthermore, the crystal structure analysis of ALAS from Rhodobacter capsulatus [ 23] suggests that a missense mutation at Arg170 destabilizes PLP binding, which might be partially restored with excess amounts of PLP.
The idea that Gal-4 might restore naturally occurring anti-inflammatory systems which are defective in IBD was substantiated by our observation that Gal-4 potently induces PBT, but also LPT apoptosis.
House Republican leaders said today that they might restore President Bush's ability to choose which agency supervises the reconstruction, a decision that could allow the Pentagon to take charge of an effort that would normally be handled by the State Department.
This leads to an apparent paradox, with the abundant synovial vasculature (which might be expected to restore oxygen levels to normal) occurring nonetheless together with regions of synovial hypoxia.
