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Signatures of different cell types, even within a given tissue, can easily mask true differences between groups [ 30, 43], or, as we have shown, spuriously contribute to differences which may truly exist.
This seems to be yet another basis for thinking that any cortical column based upon the terminations of topographically organized bundles of thalamic axons can be broken down into smaller groupings of cells which retain the fundamental vertical connectivity, such as demonstrated in a more general way in the present set of papers and which may truly be called minicolumns.
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Most of the filter design criteria and codes are based on tests from uni-directional flow conditions, which may not truly reflect the cyclic flow of in situ tidal conditions.
Many say that being authentic is key, but like I showed in the Kardashian example above, we don't prefer people who share every aspect of their life, which may be truly the authentic them.
First, this animal model provided only an acute model of IDD, which may not truly represent the process of human disc degeneration.
A potential limitation of this study is the use of TMA cores for analysis, which may not truly represent the whole tumor.
First, this study was conducted in EBV-transformed lymphoblastoid cell lines and therefore it should be noted that the differential gene expression being ascribed to drug treatment are on the background of an EBV transformation, which may not truly reflect clinical changes.
On the other hand, because stratovolcanoes can lie dormant for very long periods before again becoming active (e.g., Connor et al. 2006), we include deeply incised, radially symmetric edifices that do not preserve other morphology indicating active volcanism, some of which may be truly extinct.
Therefore, we hypothesise that the measurement of CD4 cell count alone is serving as a proxy marker for impaired humoral immunity and that it is the latter which may be truly responsible for the predisposition of HIV infected patients to acquire C. difficile disease.
Despite the Eyelink system's high resolution, our use of gaze position data (rather than eye rotation angles) may introduce slight inaccuracies in the velocity calculation, which may not be truly representative of eye rotation velocity i.e. our measure reflects more accurately the speed of gaze displacement across the screen.
The non-cancer volunteer cohort was accrued from the hospital environment, which may not be truly reflective of the general population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com