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This is a pure immunohistochemical study without molecular work-up, which may limited the understanding of the biological aspects of the findings.
We also did not differentiate unprotected safer sex practices such as serosorting, strategic positioning and withdrawal before ejaculation from UAI, which may limited our ability to understand the current drivers of HIV transmission in the community.
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This study has some limitations which may limit the generalisability of our results.
On the other hand, some limitations are found which may limit the generalizability of the results.
Also, our decedents are from limited birth cohorts (1920s 1940s), which may limit inferences to different time periods.
However, these nonspecific immunosuppressive drugs possess several significant limitations and side effects which may limit their long-term uses[2], [3].
A limitation is the 35% response rate which may limit the representativeness of the findings.
A second limitation is the small sample size, which may limit ability to generalize the results to a larger population.
Limitations include that only public facilities were included, which may limit generalizability.
Although there are a lot of positive results, there were still limitations of this study including (i) a non-random sampling which may limit generalizability, and (ii) test-retest was not performed which may limit reliability.
With earlier detection, these children could get earlier interventions, which may limit the severity of the condition".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com