Sentence examples for which may antagonize from inspiring English sources

Thus, by inhibiting Tankyrase activity, Axin is spared from the consequent ubiquitination and degradation, which may antagonize Wnt signaling and inhibit tumor growth.

In addition, resveratrol activates sirtuins [ 2, 24- 25] and AMPK [ 6, 26], which may antagonize the TOR pathway downstream and upstream, respectively.

The D7 proteins have been shown to bind biogenic amines such as serotonin and histamine, which may antagonize the vasoconstriction, platelet aggregation, and pain induction that occur during feeding [ 34].

By contrast there is a much more rapid dissociation from M2 receptors and this kinetic selectivity avoids prolonged blockade of pre-synaptic M2 receptors thus reducing the increased release of acetylcholine which may antagonize the bronchodilator effect of blocking the M3 receptors.

We hypothesize that inhibition of HDACs by SAHA leads to up-regulated expression of POLR3-mediated transcripts including tRNAs, which in turn may antagonize its anti-tumor activity.

A recent interesting discovery about lncRNA indicated that SRA is a bifunctional transcript, with one isoform functioning as an ncRNA and another as an mRNA that is translated into the protein SRAP [ 69, 70], which may in turn antagonize the function of its noncoding counterpart [ 71].

These results suggest that Msn may antagonize JNK signaling, which, to our knowledge, has only been observed once.

LIP, which lacks the transactivation domain of LAP, may antagonize the effect of low levels of endogenous C/EBPβ present in B13 cells and promote their ductal differentiation.

However, principles of receptor pharmacology predict that compounds which compete for the same receptor site may antagonize each other so that the overall response is less than additive.

Duan et al. [ 29] had reported that α-ZAL may antagonize homocysteine-induced ROS accumulation, which may contribute to α-ZAL-induced beneficial effect on endothelial function.

Lactobacilli may antagonize pathogens by several mechanisms which involve production of antimicrobial compounds such as lactic acid, acetic acid, hydrogen peroxide, and bacteriocins, competition for substrate, and coaggregation with pathogens [ 24– 27].