Your English writing platform
Discover LudwigSuggestions(4)
Exact(7)
In response to declining estrogen levels, women can lose substantial amounts of bone mass in the decade following menopause, which markedly increases their fracture risk [ 1].
Moreover, the oxidative and inflammatory burden is further magnified in metabolic syndrome, which markedly increases the risk of diabetes and cardiovascular and cerebrovascular disease in obese adults (4– 6).
We subsequently revealed for the first time the expression of SIRT1 in human NP cells, which markedly increases in IVDs during early degeneration stages, thereby promoting extracellular matrix (ECM) metabolism and cell proliferation [ 13].
Other work using skeletal muscle transgenic strategies has shown that Stim1 overexpression, which markedly increases store-operated calcium entry, is pathogenic in skeletal muscle and induces fulminant MD (Table 2).
Acute HIV infection (AHI the weeks to about 2 months between acquisition of HIV and completion of seroconversion is characterized by extremely elevated concentrations of HIV RNA (viral load) in blood and genital secretions, which markedly increases risk of transmission.
In addition, chromatin immunoprecipitation assays demonstrated that the promoter has a low basal level of histone acetylation, which markedly increases upon treatment of the cells with trichostatin A, further validating the use of this system for screening efforts to identify epigenetic modulators.
Similar(53)
Substance dependence likely leads to tolerance, in which markedly increased amounts of a drug (or other addictive substance) must be taken to achieve the same effect.
The expression levels in histocultures were constant over time and similar to the expression levels at excision except for IL-6 and IL-8, which markedly increased following the first 24 h of culture, possibly due to the initial stress.
After 2 weeks, the posts were reinforced with metal braces, which markedly increased afterload of the spontaneously beating EHTs.
Acetylation of histone 3 at lysine 9 occurred in PEER and SUPT1 cells exposed to 5 n m romidepsin, which markedly increased at 10 n m.
Since the diabetogenic effect of the Zfp69 locus required obesity, we challenged control and B6-Tg(Zfp69) mice with a HFD, which markedly increased body weight.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com