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Similar results were obtained using the transplantation model after treatment with the low molecular weight heparin derivative Clexane which markedly enhanced transplant size.
HEK-293 cells were stimulated with phorbol ester, which markedly enhanced ERK as well as RSK phosphorylation and activity.
One more advantage of our system is due to the observed strong additive effect of switched on Jurkat-TRAIL cells with chemotherapeutic agents, which markedly enhanced the toxicity of cisplatin and doxorubicin in BJAB cells, similar to other reports describing a synergistic action of recombinant TRAIL protein with cytotoxic drugs and γ-irradiation (Bonavida et al, 1999; Keane et al, 1999).
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Secondly, the length of the targets exceeds that of the probes typically by more than one order of magnitude which markedly enhances their propensity for intramolecular folding and intermolecular duplexing reactions in solution in a sequence-dependent fashion with consequences for their effective interactions with the probes.
The interaction of eIF4G with eIF4E and PABP circularizes the mRNA (by bringing together its 5'- and 3'-ends), which markedly enhances its translation.
Although youth treated with SGAs seldom develop diabetes because of their large insulin reserve, they often develop insulin resistance and dyslipidemia, which markedly enhance the risk for long-term morbidity and mortality.
This hypothesis is further supported by the found increase in systemic GCL activity in the probiotic pre-treated group, which was markedly enhanced already before the induction of AP.
In unstimulated cells, both receptors exhibited a minimal degree of phosphorylation, which was markedly enhanced in response to the addition of rhIGFs to the culture medium.
The present study demonstrated that LPS increased TNF-α production in adult ventricular myocytes, which was markedly enhanced by DOB treatment.
Induction of BimEL by 4-OHT triggered apoptosis in Mel-RM.Bim cells, which was markedly enhanced by cotreatment with TM, suggesting that melanoma cells are sensitive to ER stress-induced apoptosis provided Bim is expressed at relatively high levels.
This result is confirmed by caspase-3/7 activity assay, which showed GAP159 markedly enhanced CDDP induced caspase-3/7 activities (Fig. 3C).
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