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"And this is the way which makes changes irreversible.
From a paleontological standpoint, diversification of many orders occurred over a relatively short period of time [ 1], which makes changes in form even more curious.
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It just makes everyone stressed out, which makes change even harder.
Chiller manufacturers must be able to offer in their product ranges more customizable products with multiple options of product variants (based on a known product platform), which make changes to product design highly complicated.
The class action suit is about much more than just Walker and the city of Calhoun, which made changes to its bail practices following the litigation.
Each household member had influence over food choices for everyone, which made changes difficult to implement when not everyone wanted to alter their diet.
Antibody prevalence decreased in 2005 2006, and antibody titers decreased to values near the cut-off point, which made changes in antibody status difficult to interpret.
As a result, bills like the Patents Amendment Bill (drafted 2000) and the Industrial Property Bill (drafted 2001), both of which make changes to the current patent legislation, have been drafted and are awaiting discussion in parliament.
In a real-world scenario, there are several problems which make change detection a more challenging problem than a simple moving/static classification.
eXtreme Programming creates software using a test-first methodology, which makes frequent changes less risky.
The L1 open reading frames were codon optimized using Primo Optimum 3.4 (http://www.changbioscience.com/primo/primoo.html), which makes synonymous changes to optimal codons within the nucleotide sequence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com