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The next stage in this strategy is to optimise these fragments to more potent compounds, by adding substituents which make further binding interactions with the enzyme active site.
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This is a heatwave which makes further, hotter heatwaves more likely in the future.
Can you also reassure me that MPS officers investigating these allegations did not come under any internal pressure to weaken their investigation?" Labour's letter follows a New York Times piece which made further allegations about the scandal.
Swathes of northern Iraq have been seized by fighters for the Islamic State of Iraq and the Levant (Isis), which made further gains today, but Khamenei said he was against the US getting involved, with or without Iran's cooperation.
"Intervening in the last hour of the official campaign, this operation is obviously a democratic destabilization, as has already been seen in the United States during the last presidential campaign," Macron's staff said Friday night, minutes before the start of a strict curfew on campaigning, which made further public response off-limits.
Les Ebdon, chairman of million+, the group that represents new universities, says: "For universities this is a phoney war because this funding settlement could be completely blown out of the water if there is a second Budget after the general election which makes further cuts to higher education.
In the Civil War, the steady pressure of the blockade reduced the Confederacy to a degree of destitution which made further support of her armies impossible.
The reason for this behavior is that the islands strain the substrate compressively at their periphery, which makes further accumulation of Ge at such lattice sites unfavorable[26].
This is in line with the so-called Solange judgments of the German Constitutional Court, which made further integration and ceding of sovereignty conditional on democratization.
Also, use of cluster analysis as an initial task for any accident data analysis removes the heterogeneity of the data to some extent, which makes further analysis of the data easier.
The last adaptation of the BRAM is used by Malottki et al. [72] which made further improvements to the model by allowing for a non-linear translation of HAQ-scores to utility values and enabling probabilistic sensitivity analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com