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These phenomena ranged from small local changes eg mutations of residues in the active site (which modified chemistry or substrate specificity) or insertions of residues around the active site (which largely affected binding of substrates); through to fusions of domains with different partners (which could in turn modify active site geometries).
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The British Medical Association said the issue – which largely affects the elderly – urgently needed addressing.
Nor is it clear why the rate of thyroid cancer, which largely affects young people, is rising, said Dr. R. Michael Tuttle, an endocrinologist and thyroid cancer expert at Memorial Sloan-Kettering Cancer Center.
By changing the calculations, the rules, which largely affect oil refineries and pharmaceutical and chemical plants, could postpone requirements to upgrade pollution controls.
Many see the law, which largely affects organisations most likely to be vocal critics of the Israeli government, as a blatant attempt to target CSOs uncovering human rights violations committed by the authorities.
In Florida, where Governor Rick Scott beat Charlie Crist by a 1.2-point margin, lawymakers have passed a host of new laws, including limits on voter-registration drives (which largely affect black and Hispanic voters), reductions on early voting and a law that makes it harder for voters who move to stay registered.
Snap has since confirmed these layoffs, which largely affect those on the content teams in the New York and London offices.
The telescope is a key optical component which largely affects the signal intensity in coherent Doppler Lidar.
However, a notable problem emerged in the current IR systems is that the input queries are usually too short and too ambiguous to express their actual idea which largely affects the performance of IR systems.
In addition, the radiation pattern of body waves, which largely affects the spatial amplitude pattern in the low frequency band, is distorted at frequencies over 1 Hz mainly due to the seismic wave scattering and diffraction within the heterogeneous crust (e.g., Liu and Helmberger 1985; Takemura et al. 2016).
This disease ― which largely affects poor populations in Africa and can cause 2- to 3-foot worms to grow in people's bodies ― is close to being wiped out worldwide.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com